This book provides a detailed description of various multidimensional chromatographic separation techniques. The editor first provides an introduction to the area and then dives right into the various complex separation techniques. While still not used routinely comprehensive chromatography techniques will help acquaint the readers with the fundamentals and possible benefits of multi-dimensional separations coupled with mass spectrometry. The topics include a wide range of material that will appease all interested in either entering the field of multidimensional chromatography and those looking to gain a better understanding of the topic.
1 Introduction 1
2 Multidimensional Gas Chromatography: Theoretical Considerations 13
3 Multidimensional Liquid Chromatography: Theoretical Considerations 65
4 History, Evolution, and Optimization Aspects of Comprehensive Two-Dimensional Gas Chromatography 93
5 Flow-Modulated Comprehensive Two-Dimensional Gas Chromatography 145
6 Comprehensive Two-Dimensional Gas Chromatography Combined with Mass Spectrometry 171
7 Detector Technologies and Applications in Comprehensive Two-Dimensional Gas Chromatography 243
8 History, Evolution, and Optimization Aspects of Comprehensive Two-Dimensional Liquid Chromatography 281
9 Comprehensive Two-Dimensional Liquid Chromatography Combined with Mass Spectrometry 331
10 Comprehensive Two-Dimensional Liquid Chromatography Applications 391
11 Other Comprehensive Chromatography Methods 429
12 Comprehensive Chromatography Data Interpretation Technologies 449
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Luigi Mondello is an expert in the field of multidimensional chromatography. He has published a number of books and papers in his field and has been an invited speaker at a number of conferences. He is Editor of the "Journal of Separation Science" (Wiley). Recently he was awarded The Chromatographic Society's Silver Jubilee Medal award for his work in the field of chromatography and the COLACRO Medal for his contribution to the development and diffusion of the Chromatographic Techniques, and the HTC-Award for the most outstanding and innovative work in the field of hyphenated chromatographic techniques from the Flemish Chemical Society. He is currently Full Professor of Analytical Chemistry at the the University of Messina in Italy and permanent member of the scientific committee of the International Symposium on Capillary Chromatography (ISCC); the International Symposium on Essential Oils (ISEO); the International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-11); the Brazilian Symposium on Chromatography and Related Techniques (SIMCRO); and the Congresso Latino-Americano de Cromatografia e Tecnicas Relacionades (COLACRO).