Many current questions in biology are probed by using a range of biophysical methods, often in tandem. These increasingly powerful and sophisticated tools allow us to study the structure and dynamics of the complicated mixture of interacting molecules that make up the living cell.
"Biophysical Techniques" explains in a readily-accessible way the basics of the various methods available - including those used to study molecular structure, cell structure, and dynamic interactions - so that students can understand the principles behind the different methods used, and begin to appreciate which tools can be used to probe different biological questions, and the pros and cons of each.
Exploring the latest enhancements to classical techniques, and introducing computational techniques that have emerged relatively recently, the book provides a broad survey of the range of techniques now at the disposal of an investigator.
1: Introduction
2: Interactions and thermodynamics
3: Molecular transport
4: Spectroscopy
5: Magnetic resonance
6: Scattering and diffraction
7: Microscopy and single molecules
8: Computational methods
Iain Campbell is a Professor of Structural Biology in the Department of Biochemistry at the University of Oxford, and Emeritus Research Fellow of St John's College, Oxford. A member of the Department of Biochemistry since 1976, Iain has a long-held interest in the use of physical tools to find out how the machinery of the cell operates.