Experimental Toxicology The Basic Issues

About this book

Important text for undergraduates, post-graduates and professionals involved with studying or teaching this often controversial subject.

Contents

Effects of physical form, route and species, A. Wilson; influence of animal species, strain, age, hormonal and nutritional status, F. Roe; experimental design, A. Wilson; the biochemical principles of toxicology, W. Aldridge; animal husbandry, A. Lansdown; inhalation toxicology, R. Riley and D. Conning; histopathology in safety evaluation, J. Evans and W. Butler; the metabolism and disposition of xenobiotics, S. Gangoli and J. Phillips; theory and practice in metabolic studies, J. Phillips and S. Gangoli; immunotoxicology - conceptual problems, H. Amos; perspectives - the evaluation of reproductive toxicity and teratogenicity, A. Lansdown; genetic toxicology, D. Anderson; molecular toxicology, P. Rumsby; testing for carcinogenicity, P. Grasso; in vitro methods for teratology testing, D. Anderson; assessing chemical injury in the reproductive system, S. Gangoli and J. Phillips; statistics, P. Lee; risk assessment of chemicals, D. Lovell; epidemiology, G. Paddle; information and consultancy services in toxicology, D. Conning; regulations and advisory requirements in relation to food, D. Conning; the influence of a growing environmental awareness on toxicology laboratory design, D. Anderson and B. Copeland; good laboratory practice, R. Hawkins; ethics in experiments on animals, D. McGregor.

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