Isolation, Migration and Health

About this book

This special symposium volume of the SSHB explores the biological effects of human isolation and migration, and how the situations to which they give rise help to elucidate a variety of biological problems, ranging from evolutionary change to disease etiology. The majority of the case studies presented here are by Asian investigators, and provide a uniquely accessible source of information. Besides documenting the results, the book illustrates the different methods employed in such studies. It will be invaluable to those contemplating similar investigations elsewhere, and will be of interest to researchers in a range of disciplines including epidemiology, clinical medicine, demography, anthropology, genetics and evolutionary biology.

Contents

Preface; 1. The legacy of the IBP - Presidential Address; 2. The distinction between primary and secondary isolates; 3. Time trends in the break-up of isolates; 4. Factors influencing the frequency of consanguineous marriages in Japan; 5. Break-up of isolates; 6. Isolates in India, their origin and characterisation; 7. Consanguineous marriages and their genetical consequences in some Indian populations; 8. Biomedical and immunogenetic variation in isolated populations in India; 9. Genetic distance analyses in Israeli groups using classical markers and DNA polymorphisms in the B globin gene; 10. Non random distribution of Gm haplotypes in northern Siberia; 11. Allele frequency estimation; 12. Genetic affinities of human populations.

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