Taxus The Genus Taxus

About this book

Concentrates on taxoids from their occurrence in clinical studies, including chemistry, physical methods for structure identification, structure-activity relationships, biosynthesis, plant tissue culture, pre-clinical investigation, analytical aspects, and commercial cultivation. Taxoid synthesis is explained in considerable detail. Includes a review of the key literature, as well as data from scientists who are engaged in current taxoid research.

Contents

1. Introduction 2. Biosynthesis of Taxoids 3. Taxoids Occurring in the genus Taxus 4. Physical Methods for Identifying the Structures of Taxoids 5. Plant Tissue Culture of Taxoids 6. The Commercial Cultivation of Taxus Species and Production ofTaxoids 7. Analytical Aspects of Taxoids 8. Chemistry of Taxol and Related Taxoids 9. Total Synthesis of Taxoids 10. Structure-Activity Relationships of Taxoids 11. Pre-clinical and Clinical Investigation of the Taxanes 12. Paclitaxel Content of Yews inIreland

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