A thorough appreciation of the cellular, molecular and tissue changes which precede the birth of an animal is a fundamental requirement for understanding normal structural development and also abnormal processes which result in congenital defects. This textbook provides information relevant to many subjects taught in preclinical, paraclinical and clinical years. Early chapters describe and explain sequential events relating to the division, growth and differentiation of cells and to the formation of foetal membranes, implantation and placentation. Succeeding chapters trace the origin, growth, development and maturation of the major body systems. Age determination of the embryo and foetus is reviewed in a single chapter. Genetic, chromosomal and environmental factors which adversely affect pre-natal development are reviewed in the final chapter. A reading list at the end of each chapter offers additional sources of information on the topics discussed. Tables, flow diagrams and numerous hand-drawn illustrations provide information in a form which complements the concepts presented in the text.
Preface
Acknowledgements
1 Division, growth and differentiation of cells
2 Gametogenesis
3 Fertilisation
4 Cleavage
5 Gastrulation
6 Aspects of cell signalling and gene functioning during development
7 Establishment of the basic body plan
8 Coelomic cavities
9 Foetal membranes
10 Forms of implantation and placentation
11 Cardiovascular system
12 Embryological and post-natal features of haematopoiesis
13 Nervous system
14 Muscular and skeletal systems
15 Digestive system
16 Respiratory system
17 Urinary system
18 Male and female reproductive systems
19 Structures in the head and neck
20 Endocrine system
21 Eye and ear
22 Integumentary system
23 Age determination of the embryo and foetus
24 Genetic, chromosomal and environmental factors which adversely affect pre-natal development
Glossary
Index