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This is a lab manual intended for use in undergraduate courses and some graduate courses. It contains open-ended experiments to teach applied bacteriology approaches and techniques. Included are the fundamental principles of bacteriology, microbial ecology, bacterial physiology, basic fermentation, and biocontrol. There is no other lab manual of this kind in the market. It breaks new ground in hands-on bacteriology, emphasizing the role of bacteria in both microbiological and macrobiological disciplines. This is also one of the few lab books stressing the use of invertebrate animals as bacteriological material. It presents an open-ended experimental design. The experiments included are multi-disciplinary, featuring applied bacteriology procedures. It is applicable to bacteriology and macrobiology courses and the experiments can be used singly or in multiple array. It is suitable for individual or class. It offers alternate or parallel experiments. Laboratory lore integrating experiment background with insightful explanations. It stresses the use of insects, mollusks, and other invertebrates as lab animals vis-a-vis bacteriological materials. Extensive sources, resources, and references are given of material as well as the livestock used in the experiments.