This new edition of a highly respected work brings together the mathematical models, embryological experiments and molecular biology relating to how the body plan of an embryo emerges from a fertilized egg.
Preface to the second edition; Preface to the first edition; 1. Regional specification in animal development; 2. The concepts of experimental embryology; 3. Theoretical embryology; 4. Hierarchies of developmental decisions; 5. Development with a small cell number; 6. Models for man: the mouse and the chick; 7. The breakthrough; 8. What does it all mean?; Appendix: How to write a program for development; References; Index.
One of the best and clearest explications of the bewildering terminology of embryology that I have ever come across...It would be difficult to find another book where the central facts of early embryonic development are set forth so clearly and economically...Slack establishes himself as an excellent expositor and critic of biomathematical theory. Cell "The tone of the discussion is non-partisan as between competing theories, but thoughtful and often provocative. Many questions are posed for the reader to ponder, where other authors might peddle their own pet speculations...it is entertainingly written; it gives a clear and refreshing perspective on a major problem; and, above all, it stimulates thought." Nature "...a singular and critical exploration of a central development problem, uncluttered by superfluous detail and, apart from the occasional bias, rigorous in evaluation of the evidence. The unpatronizing, bossy style draws the reader into the problem and it is one of those unusual science books that one can actually read rather han refer to." Rosa Beddington, Trends in Genetics