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Unique in in its focus on eukaryotic molecular biology, this textbook provides a distillation of the essential concepts of molecular biology, supported by current examples, experimental evidence, and boxes that address related diseases, methods, and techniques. End-of-chapter analytical questions are well designed and will enable students to apply the information they learned in the chapter. A supplementary website include self-tests for students, resources for instructors, as well as figures and animations for classroom use.
Preface
1. The Beginnings of Molecular Biology
2. The Structure of DNA
3. Genome Organization: From Nucleotides to Chromatin
4. The Versatility of RNA
5. From Gene to Protein
6. DNA Replication and Telomere Maintenance
7. DNA Repair and Recombination
8. Recombinant DNA Technology and Molecular Cloning
9. Tools for Analyzing Gene Expression
10. Transcription in Prokaryotes
11. Transcription in Eukaryotes
12. Epigenetics and Monoallelic Gene Expression
13. RNA Processing and Post-Transcriptional Gene Regulation
14. The Mechanism of Translation
15. Genetically Modified Organisms: Use in Basic and Applied Research
16. Genome Analysis: DNA Typing, Genomics, and Beyond
17. Medical Molecular Biology
Glossary
Index
Fundamental Molecular Biology by Lizabeth Allison is a clearly written, engaging text that provides an excellent introduction to the field of molecular biology. With numerous well-conceived diagrams and examples of real life applications, Allison's text will be appreciated by students and instructors alike. Daniel P. Herman, University of Wisconsin-Eau Claire "Lizabeth Allison's examination of molecular biology flows like a novel, which should qualify her as a non-fiction story-teller. She has mastered the art of explaining difficult concepts in a simplified and understandable manner, making this knowledge more accessible and non-threatening to students of all levels. Gems like the historical perspectives, focus boxes, and disease boxes add even more interest to this already well-written textbook." Hao Nguyen, California State University, Sacramento "Fundamental Molecular Biology is pleasingly up to date in this rapidly advancing field, and its combination of history, relevance and technical detail makes it an attractive book for lecturers and their students." Times Higher Education Supplement
