All Shops

Go to British Wildlife

6 issues per year 84 pages per issue Subscription only

British Wildlife is the leading natural history magazine in the UK, providing essential reading for both enthusiast and professional naturalists and wildlife conservationists. Published six times a year, British Wildlife bridges the gap between popular writing and scientific literature through a combination of long-form articles, regular columns and reports, book reviews and letters.

Subscriptions from £25 per year

Conservation Land Management

4 issues per year 44 pages per issue Subscription only

Conservation Land Management (CLM) is a quarterly magazine that is widely regarded as essential reading for all who are involved in land management for nature conservation, across the British Isles. CLM includes long-form articles, events listings, publication reviews, new product information and updates, reports of conferences and letters.

Subscriptions from £18 per year
Academic & Professional Books  Evolutionary Biology  Evolution

Gene-Environment Interactions Fundamentals of Ecogenetics

Edited By: Lucio G Costa and David L Eaton
557 pages, illus
Gene-Environment Interactions
Click to have a closer look
Select version
  • Gene-Environment Interactions ISBN: 9780471467816 Paperback Apr 2006 Usually dispatched within 4 days
Selected version: £116.00
About this book Contents Customer reviews Biography Related titles

About this book

Ecogenetics can be defined as the study of genetic determinants that dictate susceptibility to environmentally-influenced adverse health effects. The explosion in new, high throughput techniques for identifying genetic variants, coupled with the realization that the majority of human diseases arise through a complex interplay of genetics and environment has led to remarkable growth and interest in the field of ecogenetics. The first section of this book covers fundamental aspects of ecogenetic, such as history of the discipline, a discussion of the molecular tools currently available to assess genotypes and their pros and cons, the use of such measurements in molecular epidemiology studies, and considerations on how knowledge acquired in pharmacogenetics can be applied to ecogenetics. The second section discusses key genetic polymorphisms relevant for ecogenetics. The third section presents a disease-based approach, to address the question of how genetic polymorphisms can influence gene-environment interactions relevant to determining susceptibility to the disease. These core chapterss address various types of cancers, neurodegenerative diseases, cardiovascular disease, diabetes and obesity.


Foreword.Acknowledgments.Contributors.PART I.Chapter 1. Introduction (Lucio G. Costa and David L. Eaton).Chapter 2. Ecogenetics: Historical Perspectives (Gilbert S. Omenn and Arno G. Motulsky).Chapter 3. Tools of Ecogenetics (Theo K. Bammler, Federico M. Farin, and Richard P. Beyer).Chapter 4. Epidemiologic Approaches (Harvey Checkoway, Parveen Bhatti, and Anneclaire De Roos).Chapter 5. Statistical Issues in Ecogenetic Studies (Stephanie A. Monks).PART II.Chapter 6. Overview of Section II (Lucio G. Costa and David L. Eaton).Chapter 7. Polymorphisms in Cytochrome P450 and Flavin-Containing Monooxygenase Genes (Catherine K.Yeung, Allan E. Rettie, and Kenneth E. Thummel)Chapter 8. Polymorphisms in Xenobiotic Conjugation (Helen E. Smith, David L. Eaton, and Theo K. Bammler).Chapter 9. Paraoxonase, Butyrylcholinesterase, and Epoxide Hydrolase (Lucio G. Costa, Toby B. Cole, Gary K. Geiss, and Clement E. Furlong).Chapter 10. DNA Repair Enzymes (Jon P. Anderson and Lawrence A. Loeb).Chapter 11. Receptors and Ion Channels (Lucio G. Costa).PART III.Chapter 12. Overview of Section III (Lucio G. Costa and David L. Eaton).Chapter 13. Lung Cancer (Valle Nazar-Stewart).Chapter 14. Gastrointestinal Cancers (Thomas L.Vaughan).Chapter 15. Neurodegenerative Diseases (Samir N. Kelada, Harvey Checkoway, and Lucio G. Costa).Chapter 16. Cardiovascular Disease (Melissa A.Austin and Stephen M. Schwartz).Chapter 17. Type 2 Diabetes (Karen L. Edwards).Chapter 18. Infectious Disease Ecogenetics (David R. Sherman).Chapter 19. Genetic Variation, Diet, and Disease Susceptibility (Johanna W. Lampe and John D. Potter).Chapter 20. Genetic Determinants of Addiction to Alcohol, Tobacco, and Drugs of Abuse (Andrew J. Saxon).PART IV.Chapter 21. Overview of Section IV (Lucio G. Costa and David L. Eaton).Chapter 22. Ethical Issues in Ecogenetics (Kelly Fryer-Edwards, Lindsay A. Hampson, Christopher R. Carlsten, and Wylie Burke).Chapter 23. Social and Psychological Aspects of Ecogenetics (Deborah Bowen, Shirley Beresford, and Brenda Diergaarde).Chapter 24. Legal Issues (Kate Battuello and Anna Mastroianni).Chapter 25. Risk Assessment and the Impact of Ecogenetics (Elaine M. Faustman and Gilbert S. Omenn).Bibliography.Index.

Customer Reviews


Lucio G. Costa, Ph.D., is professor of environmental health and toxicology at the University of Washington School of Public Health and Community Medicine. He is also director of the NIEHS-sponsored Neurotoxicology Research Core at the Center in Ecogenetics and Environmental Health. His research is focused on the study of the cellular, biochemical and molecular mechanisms involved in neurotoxicity using biochemical, molecular and imaging techniques. David L. Eaton is Professor of Environmental Health and Associate Dean for Research in the School of Public Health and Community Medicine at the University of Washington. He serves as Director of the Center for Ecogenetics and Environmental Health, and is also Deputy Director for a major NIEHS-sponsored research initiative in the area of toxicogenomics. Dr. Eaton's research interests focus on understanding how subtle genetic differences between individuals and species can result in potentially large differences in susceptibility to chemical carcinogens.
Edited By: Lucio G Costa and David L Eaton
557 pages, illus
Media reviews
...a must-have for all toxicology and pharmacology students as well as a great resource for researchers and physicians. (Environmental Health Perspectives, June 2006) "...a vital in-office reference for any scientific researcher dedicated to the study of genetics...invaluable to public health researchers who are look at how global threats live Avian Flu might spread to the general indispensable reference to all health science libraries." (The Electric Review, March/April 2006)
Current promotions
Backlist BargainsThe Mammal SocietyOrder your free copy of our 2018 equipment catalogueBritish Wildlife