Books  Ecological & Biological Sciences  Animal & General Biology  Biochemistry & Molecular Biology 

Gene Probes: A Practical Approach, Volume 2: Applications

Handbook / Manual

Series: Gene Probes: A Practical Approach Volume: 2

Edited By: BD Hames and SJ Higgins

414 pages, 37 b/w photos, 24 line illus

IRL Press

Paperback | Nov 1995 | #48492 | ISBN: 0199634149
Availability: Usually dispatched within 2-3 weeks Details
NHBS Price: £69.99 $92/€79 approx
Hardback | Dec 1995 | #48493 | ISBN: 0199634157
Out of Print Details

About this book

Gene probes find a wide variety of uses in molecular biology, and are essential tools for genetic research. This volume describes some of their many applications, from the study of nucleic acids, through blotting techniques and gene targeting, to the analysis of human genetic mutations. A companion volume covers the preparation of these probes. The volumes aim to contribute to a growing field of research.


1. Hybridization strategy; 2. Screening recombinant DNA libraries by hybridization and amplification; 3. Screening human recombinant libraries with nucleic acid probes; 4. Antibody screening of bacterial expression systems; 5. Isolation of cDNA clones by direct expression in mammalian cells; 6. Genomic mapping and gene structure analysis; 7. Analysis of gene expression by blotting techniques; 8. In situ hybridization of nucleic acid probes to cellular RNA; 9. Applications of chromosomal in situ hybridization; 10. Analysis of gene expression analysis by PCR: a quantitative approach; 11. Analysis of protein expression by immunocytochemistry; 12. Gene targeting in mammalian cells; 13. Directed mutagenesis and mutant analysis; 14. Human gene mutational analysis; Appendix 1; Appendix 2

Write a review

There are currently no reviews for this book. Be the first to review this book!

Bestsellers in this subject

C. Elegans II

NHBS Price: £58.99 $78/€67 approx

RNA Biology

NHBS Price: £54.99 $73/€62 approx

Biochemistry: A Short Course

NHBS Price: £53.99 $71/€61 approx

Organic Chemistry Study Guide and Solutions

NHBS Price: £44.99 $59/€51 approx

Ancestral Sequence Reconstruction

NHBS Price: £102.50 $135/€116 approx

VAT: GB 407 4846 44
NHBS Ltd is registered in England and Wales: 1875194