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Academic & Professional Books  Organismal to Molecular Biology  Genetics

Genome Duplication

Textbook
By: Melvin DePamphilis and Stephen D Bell
449 pages, Figs, tabs
Publisher: Garland Science
Genome Duplication
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  • Genome Duplication ISBN: 9780415442060 Paperback Nov 2010 Usually dispatched within 6 days
    £48.99
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About this book

Using model organisms from the three domains of life (Bacteria, Archaea, and Eukarya), "Genome Duplication" explains the principle molecular mechanisms of DNA replication and shows how the process is linked to cell division. This approaches allows the book to give insight into how genome duplication evolved, and how its regulation is relevant to the understanding and treatment of human disease, especially cancer. By providing a comprehensive and readable overview, "Genome Duplication" provides an excellent starting point for undergraduate and graduate students.

Contents

1. Genomes 2. Life 3. Replication Forks 4. Replication Proteins: leading strand synthesis 5. Replication Proteins: lagging strand synthesis 6. Termination 7. Chromatin Assembly Cohesion and Modification 8. Replicons 9. Replication Origins 10. Origin Paradigms 11. Initiation 12. Cell Cycles 13. Checkpoints 14. Medical Relevance 15. Evolution of Cellular Replication Machineries

Customer Reviews

Biography

National Institute of Child Health and Human Development, USA Hutchison MRC Research Centre, UK
Textbook
By: Melvin DePamphilis and Stephen D Bell
449 pages, Figs, tabs
Publisher: Garland Science
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