About this book
With contributions by two Nobel Laureates, this careful selection of high-quality articles from the Encyclopedia of Molecular Cell Biology and Molecular Medicine spans the whole range of topics in genomics and genetics.
The first volume deals with molecular genetics, genomic organization and evolution, as well as genomes of model organisms, while the second goes on to treat genomic sequencing, genetic engineering and gene medicine and disease. Throughout, the chapters conform to a uniform structure, including a keyword glossary, a summary of the article in question and a list of literature references.
The result is a readily accessible reference for geneticists, molecular biologists, biochemists, biotechnologists, pharmacologists, and developmental biologists, as well as those working in the pharmaceutical industry.
Volume 1.Preface.Color Plates.1. Molecular Genetics.1. Molecular Basis of Genetics (D. Peter Snustad).2. DNA Replication and Transcription (Yusaku Nakabeppu, Hisaji Maki, and Mutsuo Sekiguchi).3. Translation of RNA to Protein (Robert Ashley Cox Henry Rudolph Victor Arnstrin).4. Alternatively Spliced Genes (Jane Y. Wu, Liya Yuan, and Necat Havliglu).5. Repair and Mutagenesis of DNA (Raymod Devoret).6. Molecular Genetics of Genomic Imprinting (Robert Feil, Yuji Goto, and David Umlauf).7. Heterochromatin and Eurochromatin - Organization, Packaging, and Gene Regulation (Boris A. Leibovitch Sarah C. R. Elgin).2. Genomic Organization and Evolution.8. Organization of Genes and Genome Domains (Yujing Zeng, Javier Garcia-Frias, and Adam G. Marsh).9. Anthology of Hyman Repetitive DNA (Vladimir V. Kapitonov, Adam Pavlicek, and Jerzy Jurka).10. Evolution of Noncoding DNA in Eukaryotes (Josep M. Comeron).11. Horizontal Gene Transfer (Jack A. Heinemann Ralph A. Bungard).12. Molecular Systematics and Evolution (Jeffrey H. Schwartz).13. Genetic Variation and Molecular Evolution (Werner Arber).3. Genomes of Model Organisms.14. E. Coli Genome (Hirotada Mori and Takashi Horiuchi).15. Drosophila Genome (Robert D.C. Saunders).16. Malaria Mosquito Genome (Robert A. Holt Frank H. Collins).17. Zebrafish (Danio rerio) Genome and Genetics (Ralf Dahm, Robert Geisler, Christiane Nussllein-Volhard).18. Rat Genome (Rattus norvegicus) (Kim C. Worley Preethi Gunaratne).19. Chimpanzee Genome (Ingo Ebersberger).Volume 2.Preface.Color Plates.4. Genomic Technologies.20. Genomic Sequencing (Todd Charles Wood and Jeffrey P. Tomkins).21. Construction and Applications of Genomic DNA Libraries (Eugene R. Zabarovsky).22. Shotgun Sequencing (SGS) (Jun Yu, Gane Ka-Shu Wong, Jian Wang, Huanming Yang).23. Whole Genome Human Chromosome Physical Mapping (Cassandra L. Smith, Giang H. Nguyen, Denan Wang, Nickolaev Bukanov).24. Serial Analysis of Gene Expression (Jacques Marti Jean-Marc Elalouf).25. Gene Mapping by Fluorescence In Situ Hybridization (Barbara G. Beatty and Henry H.Q. Heng).26. Gene Mapping and Chromosome Evolution by Fluorescence-Activated Chromosome Sorting (Malcolm A. Ferguson-Smith).5. Genetic Engineering.27. Gene Targeting (Michael M. Seidman and John H. Wilson).28. Genetic Engineering of Antibody Molecules (Manuel L. Penichet and Sherie L. Morrison).29. Transgenic Fish (Pinwen Peter Chiou, Jenny Khoo, Chung Zoon Chun, Thomas T. Chen).30. Transgenic Mice in Biomedical Research (J. Willem Voncken Marten Hofker).31. Transgenic Plants for Food Use (Susanne Stirn Horst Lorz).6. Gene Medicine and Disease.32. Human Genetic Variation and Disease (Lynn B. Jorde).33. Alzheimer's Disease (Jun Wang, Silva Hecimovic and Alison Goate).34. Triplet Repeat Diseases (Stephan J. Guyenet Albert R. La Spada).35. Molecular Genetics of Down Syndrome (Charles J. Epstein).36. Molecular Genetics of Hemophilia (Francesco Giannelli Peter M. Green).37. Gene Therapy and Cardiovascular Diseases (Michael E. Rosenfeld and Alan D. Attie).38. Somatic Gene Therapy (M. Schweizer E. Flory, C. Munk, Uwe Gottschalk, K. Cichutek).39. Mutagenesis, Malignancy and Genome Instability (Garth R. Anderson, Daniel L. Stoler, Jeremy D. Bartos).Cumulative List of Contributors.Subject Index.
Robert A. Meyers obtained his Ph.D. in Chemistry at the University of California at Los Angeles. He was a post-doctoral fellow at the California Institute of Technology and has more than 17 patents, 50 technical papers and 12 books to his name. As Editor-in-Chief he conceived and edited several ambitious multivolume reference works, e.g. the Encyclopedia of Analytical Chemistry (Wiley), the preceding Encyclopedia of Molecular Biology and Molecular Medicine (VCH) and the Encyclopedia of Physical Science and Technology (Academic Press).