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Lee Hood did that rarest of things. He enabled scientists to see things they couldn't see before and do things they hadn't dreamed of doing. Scientists can now sequence complete human genomes in a day, setting in motion a revolution that is personalizing medicine.
Hood, a son of the American West, was an unlikely candidate to transform biology. But with ferocious drive, he led a team at Caltech that developed the automated DNA sequencer, the tool that paved the way for the Human Genome Project. He captivated scientists with his almost religious fervour for the new biology enabled by the machines.
Hood's brilliance, rebellion, enthusiasm, and ego earned him detractors as well as admirers. His management style, once described as "creative anarchy," alienated many. Some of his collaborators seethed, claiming he took too much credit. Fellow Caltech biologists charged that his empire building was out of control and ousted him as their chairman. A fraud in his lab made him consider, for a moment, quitting science.
Wooed by money from Bill Gates, Hood started over at the University of Washington, creating the world's first Department of Molecular Biotechnology. Seven years later, his impatience for rules drove him to depart. He left at age sixty-one to start his own Institute for Systems Biology. Would he finally achieve the ultimate application of the genome project – personalized medicine?
In Hood: Trailblazer of the Genomics Age journalist Luke Timmerman zeroes in on a charismatic, controversial personality. Never-before-reported details are drawn from the scientist's confidential files, public records, and more than 150 interviews with Hood and his family, friends, collaborators, and detractors. The result is not just a revealing portrait of one of the most influential biologists of our time, but a deeply human look
Luke Timmerman is an award-winning journalist who has covered biotech for more than 15 years. He is the founder and editor of Timmerman Report, an industry-leading biotech newsletter. Scientific American named him one of the 100 most influential people in biotech in 2015. He lives in Seattle with his wife and daughter. This is his first book.
"A must-read popular science book."
"A thorough biography [that] never shies away from the contradictions of this forceful personality [...] Hood deserves to be a household name."
– Kirkus Reviews (starred review)
"An engrossing look at the man, his times, the technology he brought into being and the implications for humanity."
– San Diego Union-Tribune
"A thrilling ride through the life of a visionary biologist."
– Bio-IT World
"A revealing story that should resonate beyond the biotech world."
"A masterful guide to one of the most important scientists of the 20th century."
– Genome magazine