204 pages, 16 b/w photos, 64 b/w illustrations, 29 tables
Parasites cause many important diseases in humans and domestic animals, malaria being an example. Parasites have evolved to exploit hosts' bodies whereas hosts have evolved immune systems to control infections. Host-parasite interactions therefore provide fascinating examples of evolutionary 'arms-races' in which the immune system plays a key role. Modern research in immunoparasitology is directed towards understanding and exploiting the capacity to develop effective anti-parasite immunity. By concentrating on selected infections where research has made significant progress, Immunity to Parasites provides a clear account of how host immune responses operate and how parasites can evade immunity. The experimental basis of this research is emphasised throughout. This completely updated second edition includes an expanded section on anti-parasite vaccines. The text is aimed at undergraduates and postgraduates with interests in either parasitology or immunology and provides introductory sections on these topics to lead the reader into the later chapters.
"[...] an admirable effort to introduce undergraduate and doctoral students to the immunology of parasitic infections. Clearly written and ably illustrated [...] a highly readable introduction to immunoparasitology."
- Richard Locksley, Immunology Today
"This book will, I am confident, remain at the very top of the 'hit parade' of immunoparasitology textbooks and it is a must on the bookshelf of all those interested in parasitology, immunology or infectious diseases."
- M. Hommel, Annals of Tropical Medicine and Parasitology
"Peppered with original photomicrographs and experimental data [...] useful reading for those needing general information on the ever-burgeoning field of parasite immunology."
- Thomas B. Nutman, Trends in Microbiology
" [...] the second edition of Wakelin's Immunity to Parasites represents an excellent textbook aimed at undergraduates and postgraduates interested in either parasitology or immunology as well as at medical and veterinary specialists. It was a great pleasure to teach immunoparasitology with the help of this superb, clearly written and illustrative book."
- Jan Kopecky, Folia Parasitologica
"[...] fascinating in the details of host and parasite adjustment and co-evolution."
- Dennis Cotton, Biologist
Preface to the Second Edition
Preface to the First Edition
1. Parasites and parasitism
2. The immune response
3. Experimental immunoparasitology
4. Intracellular Protozoa
5. African trypanosomes
7. Gastrointestinal nematodes
8. Nematodes which invade tissue
9. Ectoparasitic arthropods
10. Immunological control of parasitic infections
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