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In Vitro Methods in Aquatic Ecotoxicology

Handbook / Manual

By: C Mothersill and B Austin

472 pages, Illus


Hardback | Dec 2003 | #142560 | ISBN: 3540023577
Availability: Usually dispatched within 1 week Details
NHBS Price: £279.99 $370/€314 approx

About this book

This book, the first of its kind in this subject area, will focus on in vitro approaches to the study of the toxicology of polluting agents (including heavy metals, radionuclides, micro-organics, estrogenic compounds, and complex mixtures) in the aquatic environment. The importance of in vitro methods is that they allow standardised techniques to be developed and validated for substance and species specific experiments in a controlled way. Also, they allow mechanistic studies without the problems of individual variation between animals and environmental stress.


Introduction; basic culture methods for aquatic species; basic approaches in in vitro toxicology; specialised tissue culture methods; Species specific techniques; endpoints and tools; recombinant technologies, proteomics and genomics, heavy metals; micro-organis and estrogenic compounds; carcinogens and genotoxic agents; radionuclides; sediments; biotoxins; validation: in vitro in vivo bridging approaches; regulation: practical and legal issues; discussion

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