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Academic & Professional Books  Reference  Data Analysis & Modelling  Bioinformatics

Introduction to Computational Biology An Evolutionary Approach

By: B Haubold and T Wiehe
328 pages, diags
Introduction to Computational Biology
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  • Introduction to Computational Biology ISBN: 9783764367008 Hardback Dec 2006 Usually dispatched within 1-2 weeks
Selected version: £40.99
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About this book

Undergraduate textbook focusing on bioinformatics from an evolutionary point of view. Covers the following topics: gene finding by linkage disequillibrium mapping, restriction maps, DNA analysis and forensic medicine, sequence data bases, introduction to and application of pairwise alignments, Bayesian statistics, detecting sequence patterns, DNA-protein interaction, multiple alignments, phylogenetic analysis, distance methods, parismony and likelyhood, neutral theory, and coalescent theory. The volume contains exercises, questions and answers to selected problems, an introduction to coalescent theory, and an appendix with essentials of probability theory.


Optimal Pairwise Alignment.- Biological Sequences and the Exact String Matching Problem.- Fast Alignments: Genome Comparisons and Database Searches.- Multiple Sequence Alignment.- Sequence Profiles and Hidden Markov Models.- Gene Prediction.- Phylogeny.- Sequence Variation and Molecular Evolution.- Genes in Populations: Forward in Time.- Genes in Populations: Backward in Time.- Testing Evolutionary Hypotheses.- Bioinformer CD.- Probability and Statistics.- Molecular Biology Figures and Tables.- Resources.- Answer to Exercises.- References.- Glossary.- Index

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By: B Haubold and T Wiehe
328 pages, diags
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