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Over the last century, the centrality of proteins to life on earth has become increasingly clear – from forming crucial molecules such as antibodies in the immune system to acting as catalysts for specific reactions, and as signalling molecules between cells. In fact, the more they are studied, the more proteins continue to reveal new and exciting functions. Indeed, by studying amino acid sequences it is even possible to unravel some of the mysteries of evolution itself.
Introduction to Protein Science, 3rd edition provides a rich and broad introduction to this fascinating field by covering not only the structure and function of proteins, but also the methods and experimental techniques used to study them. The practical applications of our knowledge to diverse fields such as biotechnology and medicine are emphasized throughout, to help students appreciate the relevance of the subject to the real world. Active learning is encouraged by the provision of frequent exercises and problems, with further 'weblems' based on the Online Resource Centre.
New to this edition:
- The artwork has been refreshed throughout, with new online rotating structures more clearly depicting complex three dimensional structures
- Increased coverage of areas at the forefront of research, such as the regulation of protein activity and molecular dynamics
- Further emphasis on the applied aspects of protein science to enable students to see why protein science is such a hot topic in research
- Web-based problems are now online for quicker access to web links
2: Protein structure
3: Protein structure determination
4: Bioinformatics of protein sequence and structure
5: Proteins as catalysts: enzyme structure, kinetics, and mechanism
6: Proteins with partners
7: Evolution of protein structure and function
8: Protein folding and design
9: Proteomics and systems biology
Arthur M. Lesk is Professor of Biochemistry and Molecular Biology at The Pennsylvania State University. He is the author of the highly successful Introduction to Bioinformatics, and Introduction to Genomics, both published by Oxford University Press.