370 pages, photos, diagrams
Introduction to Veterinary Pathology, Third Edition, is constructed for the beginning student in veterinary pathology, to introduce new scientific information on mechanisms of general tissue injury into the language of medicine. The basic concepts of pathology are integrated into clinical medicine. Chapters on cellular degeneration and necrosis, inflammation, thrombosis, hemodynamic disorders, and neoplasia have been reconstructed to include the latest in new scientific information and color illustrations of gross pathology. The revised 3rd edition also includes new chapters on: Infectious Diseases; Nutritional and Metabolic Diseases; Ecosystems and Environmental Pathology; and, Forensic Pathology and Bioterrorism.
The new text has remained true to elements favored in a review of the 2nd edition: '...chapters cover the time-honoured topics of basic pathology...the information is impressively current and compact. Important points are illustrated with memorable examples of natural disease from the full range of domesticated species and our debt to laboratory animals is also recognized. The text is embellished with pathological vignettes such as an 1819 account of tetanus and the weaponry potential of anthrax, and the many photographs are eye-catching and often paired in order to contrast normal with abnormal or gross with microscopic' - Dr. Malcolm France, course coordinator for Veterinary Pathology, University of Sydney.
Preface Introduction 1. Overview: Injury, Death and Adaptive Responses The Language of Pathology The Diagnosis Necrosis Adaptive Responses to Injury and Altered Stimulation Pathologists at Work 2. Cell Death and Cell Recovery Necrosis: Morphology and Mechanisms Apoptosis: Programmed Cell Death Cell Protection and Recovery 3. Cellular Responses to Sublethal Injury Metabolite Overload Protein Aggregation Disorders Amyloid Calcification Pigments Crystals Connective Tissue Substances 4. Inflammation Overview Clinical Signs and Lesions Pathogenesis of Acute Inflammation Systemic Signs of Acute Inflammation Chemical Mediators of Inflammation Chronic Inflammation 5. Repair: Wound Healing and Regeneration Repair Angiogenesis Fibrosis Epithelialization Regeneration 6. Hemostasis and Thrombosis Overview Prevention of Coagulation by Normal Endothelium Platelet Aggregation Blood Coagulation Thrombosis 7. Hemodynamic Disorders Cardiovascular Disease and its Consequences Edema Hemorrhage Shock Infarction Embolism Collateral and Compensatory Circulation Vascular Shunts and Fistulae Lymphatic Blockage Ischemia 8. Neoplasia:Characterizing the Neoplasm Overview Benign vs Malignant Making the Correct Diagnosis 9. Spread, Host Responses, and Genetics of Cancer The Spread of Neoplasms Clinical Effects of Neoplasms Restraint of Neoplastic Growth The Genetic Basis of Cancer The Cancer Cell 10. Causes of Cancer Chemical Carcinogenesis Viral Oncogenesis Physical Agents Associated with Neoplasms 11. Immunologic Disorders Disorders from Reduced Innate Immunity Defects in Adaptive Immunity Hypersensitivity Disease Autoimmune Disease 12. Genetic Disorders and Teratology Overview Mutant Genes of Large Effect (Mendelian Disorders) Multifactoral (Polygenic) Inheritance Disorders Chromosomal Disorders Teratology 13. Infectious Diseases Prions Viral Diseases Bacterial Diseases Fungal and Algal Diseases Pathology of Parasitism 14. Nutritional and Metabolic Disease Nutritional Diseases Metabolic Diseases Aging 15. Ecosystems and Forensic Pathology Airborne Pollutants: inhalation toxicity Environmental Pollutants Aquatic Ecosystems Agricultural Hazards Wildlife Ecosystems: free ranging animals 16. Forensic Pathology Forensic Science Bioterrorism Index
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