About this book
Summarizes the current knowledge of mammalian genomics and offers a comparative analysis of genomes known today. This analysis includes farm, companion and lab animals.
Part 1. Organization of the Mammalian Genome; Linkage mapping, C Moran and J W James, University of Sydney, Australia; Mapping genomes at the chromosome level, B P Chowdhary and T Raudsepp, Texas A&M University, USA; Mapping genomes at the molecular level, F Galibert, Universite de Rennes, France, and N E Cockett, Utah State University, USA; DNA sequence of the human and other mammalian genomes, D Vaiman, INSERM, France; Part 2. Expression of the Mammalian Genome; The transcriptome, A Verger and M Crossley, University of Sydney, Australia; The proteome, M B Datto and T A Haystead, Duke University, USA; The epigenome - epigenetic regulation of gene expression in mammalian species, E Whitelaw, University of Sydney, and D Garrick, John Radcliffe Hospital, Oxford, UK; Regulation of genome activity and genetic networks in mammals, V Van Buren, and M S H Ko, National Institute of Health, USA; Including alterations in the mammalian genome for investigating the function of genes, J L Guenet, Institut Pasteur, France;Part 3. Evolution of the Mammalian Genome; Mammalian genomes in context, M I Bellgard, Murdoch University, Australia, and T Gojobori, National Institute of Genetics, Japan; Elements and mechanisms of genome change, R J O'Neill, G C Ferreri and M J O'Neil, University of Connecticut, USA; DNA sequence evolution and phylogenetic footprinting, E T Dermitzakis, The Wellcome Trust Sanger Institute, Cambridge, UK, and A Reymond, University of Geneva Medical School, Switzerland; The evolution of the mammalian karyotype, F Pardo-Manuel de Villena, University of North Carolina at Chapel Hill, USA; Comparative gene mapping and chromosome painting in mammals and the reconstruction of the ancestral mammalian karyotype, O L Serov, Russian Academy of Sciences, Russia, B P Chowdhary, J E Womack, Texas A&M University, USA, and J A Marshall Graves, The Australian National University, Australia;Part 4. Genome Analysis and Bioinformatics; Bioinformatics: from computational analysis through to integrated systems, M I Bellgard; Genetic databases, V Brusic and J L Y Koh, Institute for Infocomm Research, Singapore; Gene predictions and annotations, R Guido, Universitat Pompeu Fabra, Spain, and M Q Zhang, Cold Spring Harbor Laboratory, USA; Part 5. The Fruits of Mammalian Genomics; Genomic research and progress in understanding inherited disorders in humans and other mammals, D R Sargan, University of Cambridge, UK, and A I Agoulnik, Baylor College of Medicine, Houston, USA; Pharmacogenomics, W W Weber and J M Rae, University of Michigan School of Medicine, USA; Genome scanning for quantitative trait loci, B J Hayes, Agricultural University of Norway, Norway, B P Kinghorn, and A Ruvinsky, University of New England, Australia; Mammalian population genetics and genomics, L Chikhi, Universite Paul Sabatier, France, and M Bruford, Cardiff University, UK