Modern Microbial Genetics

About this book

Focuses on how bacteria and bacteriophage arrange and rearrange their genetic material through mutation, evolution, and genetic exchange to take optimal advantage of their environment. The text is divided into three sections: DNA Metabolism, Genetic Response, and Genetic Exchange.

Contents

Preface. Preface to the First Edition. Introduction. Contributors. SECTION I: DNA METABOLISM. Prokaryotic DNA Replication (W. Firshein). DNA Repair Mechanisms and Mutagenesis (R. Yasbin). Gene Expression and Its Regulation (J. Helmann). Bacteriophage Genetics (B. Guttan & E. Kutter). Bacteriophage lambda and Its Relatives (R. Hendrix). Single--Stranded DNA Phages (J. LeClerc). Restriction--Modification Systems (R. Blumenthal & X. Cheng). Recombination (S. Levene & K. Huffman). Molecular Applications (T. Geoghegan). SECTION II: GENETIC RESPONSE. Genetics of Quorum Sensing Circuitry in Pseudomonas aeruginosa: Implications for Control of Pathogenesis, Biofilm Formation and Antibiotic/Biocide Resistance (D. Hassett, et al.). Endospore Formation in Bacillus subtilis: An Example of Cell Differentiation by a Bacterium (C. Moran). Stress Shock (U. Streips). Genetic Tools for Dissecting Motility and Development of Myxococcus xanthus (P. Hartzell). Agrobacterium Genetics (W. Ream). Two--Component Regulation (K. Bayles & D. Fujimoto). Molecular Mechanisms of Quorum Sensing (C. Fuqua & M. Parsek). SECTION III: GENETIC EXCHANGE. Bacterial Transposons--An Increasingly Diverse Group of Elements (G. Whittle & A. Salyers). Transformation (U. Streips). Conjugation (R. Porter). The Subcellular Entities a.k.a. Plasmids (M. Perlin). Transduction in Gram--Negative Bacteria (G. Weinstock). Genetic Approaches in Bacteria with No Natural Genetic Systems (C. Haller & T. DiChristina). Index.

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