Molecular Biology of the Cell - The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter will review key terms, test for understanding basic concepts, and pose research-based problems. The Problems Book has been designed to correspond with the first twenty chapters of Molecular Biology of the Cell, Fifth Edition. It includes the solutions to the end-of-chapter problems in the textbook Molecular Biology of the Cell, Fifth Edition. It contains over 2000 problems and their solutions. All of the solutions to the problems in The Problems Book are on the CD-ROM that is packaged with every copy of the book. The problems are organized into the following categories: Terms to Learn, Definitions, True/False, Thought Problems, Calculations, and Data Handling. The Problems Book will be useful for homework assignments and as a basis for class discussion. It could even provide inspiration for exam questions.
1. Cells and Genomes
2. Cell Chemistry and Biosynthesis
4. DNA and Chromosomes
5. DNA Replication, Repair and Recombination
6. How Cells Read The Genome: From DNA to Protein
7. Control of Gene Expression
8. Manipulating Proteins, DNA and RNA
10. Membrane Structure
11. Membrane Transport of Small Molecules and the Electrical Properties of Membranes
12. Intracellular Compartments and Protein Sorting
13. Intracellular Vesicular Transport
14. Energy Conversion: Mitochondria and Chloroplasts
15. Cell Communication
16. The Cytoskeleton
17. The Cell Cycle and Programmed Cell Death
18. The Mechanics of Cell Division
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John Wilson received his PhD from the California Institute of Technology and did his postdoctoral work at Stanford University. He is currently Professor of Biochemistry and Molecular Biology at Baylor College of Medicine, with research interests in genome stability and gene therapy. He has taught medical and graduate students for many years, co authored books on immunology, molecular biology, and biochemistry, and received numerous teaching honors, including the Distinguished Faculty and Robertson Presidential Awards for excellence in education.
Tim Hunt received his PhD in biochemistry from Cambridge University, where he supervised undergraduates in cell biology for more than 20 years. He spent many summers in the late 1970s and early 1980s teaching molecular biology at the Marine Biological Laboratories in Woods Hole, Massachusetts. In 1990, he moved to a position at ICRF Clare Hall Laboratories just outside London, where he works on the control of the cell cycle. He is a Fellow of The Royal Society of London and a foreign associate of the US National Academy of Sciences. In recognition of his contribution to the discovery of key regulators of cell cycle, he was one of the recipients of the 2001 Nobel Prize for Physiology or Medicine.