+44 1803 865913
Edited By: Manyuan Long
204 pages, Figs, tabs
The first book to address the origin and evolution of new gene functions. 16 chapters from pioneers and leading scientists in this newly emerging field cover topics ranging from molecular mechanisms to population genetics.
Preface; M. Long. 1. The contribution of RNAs and retroposition to evolutionary novelties; J. Brosius. 2. The emergence of a synthetic theory of intron evolution; S.J. De Souza. 3. Introns in gene evolution; L. Fedorova, A. Fedorov. 4. Functional divergence in protein (family) sequence evolution; Xun Gu. 5. The EBG system of E. coli: Origin and evolution of a novel beta-galactosidase; B.G. Hall. 6. The fucosyltransferase gene family: An amazing summary of the underlying mechanisms of gene evolution; C. Javaud, F. Dupuy, A. Maftah, R. Julien, J.-M. Petit. 7. Origin of new genes: Evidence from experimental and computational analyses; M. Long, M. Deutsch, Wen Wang, E. Betran, F. Brunet, Jianming Zhang. 8. Transposable elements and vertebrate protein diversity; A. Lorenc, W. Makalowski. 9. Birth of human-specific genes during primate evolution; J.-L. Nahon. 10. Evolution by gene duplication revisited: Differentiation of regulatory elements vs proteins; T. Ohta. 11. Modular assembly of genes and the evolution of new functions; L. Patthy. 12. Origin and evolution of a new gene expressed in the Drosophila sperm axoneme; J.M. Ranz, A.R. Ponce, D.L. Hartl, D. Nurminsky. 13. Molecular mechanisms of exon shuffling: Illegitimate recombination; A.van Rijk, H. Bloemendal. 14. Recent evidence for the exon theory of genes; S.W. Roy. 15. The universe of exons revisited; S. Saxonov, W. Gilbert. 16. Population-genetic models of the fates of duplicate genes; B. Walsh.
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