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About this book
Presents the most current knowledge, ideas and speculations about the origin of the adaptive immune system and its evolution. Chapters are centered around the phylogeny of the immune system and are written by scientists who are at the forefront of research in the field.
Bridge to Invertebrates.- New Approaches Towards an Understanding of Deuterostome Immunity.- The Antimocrobial Host Defense of Drosophila.- Origin and Evolution of the Complement System.- Genome Paralogy.- Phylogeny of Lower Vertebrates and Their Immunological Structures.- Recombination-Activating Genes, Transposition, and the Lymphoid-Specific Combinatorial Immune System: A Common Evolutionary Connection.- Transcription Factor Expression in Lymphocyte Development.- The Phylogenetic Origin of Antigen-Specific Receptors.- Immunoglobulin Isotypes: Structure, Function, and Genetics.- Evolution of Vertebrate Immunoglobulin Variable Gene Segments.- The Immune System of Cartilaginous Fish.- Immune-Type Diversity in the Absence of Somatic Rearrangement.- Evolution and Somatic Diversification of Immunoglobulin Light Chains.- Evolution of the T Cell Receptor Signal Transduction Units.