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Our Genes, Our Choices: How Genotype and Gene Interactions Affect Behavior

By: David Goldman

Academic Press

Paperback | May 2012 | #198587 | ISBN-13: 9780123969521
Availability: Usually dispatched within 1-2 weeks Details
NHBS Price: £51.99 $67/€58 approx

About this book

Are people free to make choices, or do genes determine behavior? Paradoxically, the answer to both questions is "yes," because of neurogenetic individuality, a new theory with profound implications. This theory emerged from gene discoveries by Dr. Goldman and his colleagues which have been recently published in "Nature". Genetic studies reveal pathways from DNA to behavior that are helping us understand the diversity of human behavior and behavior of other species.

In this book, the complexity of human behavior and a person's ability to choose is explained as deriving from a relatively small number of genes which direct neurodevelopmental sequence. The author uses judicial, political, medical, and ethical examples to illustrate that this lifelong process is guided by individual genotype, molecular and physiologic principles, as well as by randomness and environmental exposures we choose and do not choose.

In a bold, new integrative treatment of the confusing facts and fictions about human behavior and genetic determinism, David Goldman has provided a user-friendly death to determinism and a rebirth of genetic probabilism. He uses his breadth and depth of neuroscience experience to optimize the necessary reductionism for understanding violence, impulsivity, depression, anxiety, and personality variations while explaining the newest technologies of the researcher with access to the laboratories of the National Institute of Health and his colleagues.

He bravely confronts the numerous ethical dilemmas that arise when dealing with new knowledge about our genetic makeup and their implications for good and evil.

Drawing on his personal exposure to mental disease in his own family, his sensitive and energized writing reminds me of Sylvia Nasar's explication of A Beautiful Mind", now giving us a beautiful genome from a self-described "behavioral genomicist." We are treated to an insider's knowledge about the work and hoopla about a gay gene and what may be a better conceptualization closer to the facts.

Freed from the constraints of journal writing with its 3 to 6 page shackles, Goldman tackles the utility of race as a construct without racism, communist ideology in science, insurance discrimination against the mentally ill, free will, and even pedophilia.

His work provides essential reading across the humanities, social and medical sciences, and the courtroom. As fascinating as any whodunit, he tries to account for the origins of our behavioral outcomes, for good or for evil or for mental anguish--was it genes, was it environment or culture, or bad luck, or a conspiracy among some subset of culprits? I won't give it away--read the book."

- Irving I. Gottesman Ph.D., Hon.FRCPsych, Bernstein Professor in Adult Psychiatry & Senior Fellow, Department of Psychology University of Minnesota & Sherrell J. Aston Professor of Psychology Emeritus, University of Virginia


Chapter 1: Introduction
Chapter 2: The Jinn in the genome
Chapter 3: 2B or not 2B?
Chapter 4: Stephen Mobley and his X-chromosome
Chapter 5: Dial Multifactorial for Murder: The intersection of genes and culture
Chapter 6: Distorted capacity: The measure of the impaired will
Chapter 7: Distorted capacity: Neuropsychiatric diseases and the impaired will
Chapter 8: Inheritance of Behavior and Genes "For" Behavior Gene Wars
Chapter 9: The scientific and historic bases of genethics: Who watches the geneticists and by what principles?
Chapter 10: The world is double helical DNA, RNA and proteins, in a few easy pieces
Chapter 11: The stochastic brain: From DNA blueprint to behavior
Chapter 12: Reintroducing genes and behavior
Chapter 13: Warriors and Worriers
Chapter 14: How many genes does it take to make a behavior?
Chapter 15: The genesis and genetics of sexual behavior
Chapter 16: Gene x environment interaction
Chapter 17: The epigenetic revolution: Finding the imprint of the environment on the genome
Chapter 18: DNA on Trial
Chapter 19: Parents and children: Neurogenetic determinism and Neurogenetic individuality
Chapter 20: Summing up genetic predictors of behavior

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