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PAS Proteins: Regulations and Sensors of Development and Physiology

Edited By: Stephen T Crews

Kluwer Academic Publishers

Hardback | Dec 2003 | #150857 | ISBN: 1402075863
Availability: Usually dispatched within 1-2 weeks Details
NHBS Price: £108.00 $141/€123 approx

About this book

PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen, and energy status. Not surprising, given these roles, there is intense investigation of the roles of bHLH-PAS proteins in issues of human health, including: cancer induction, cancer growth and vascularity, birth defects, including Down syndrome, appetite control and obesity, sleep rhythm disorders, and mental health disorders such as social interactions and learning. PAS proteins encompass many fields of biology, and scientists who work in these fields (circadian rhythms, oxygen regulation, toxin metabolism, bacterial sensors, and development) are an audience, particularly those who actively work on PAS proteins and researchers interested in transcriptional control, signal transduction, and evolution.

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