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Since the mid-1970s, the study of retroviruses has underpinned much of what is known about information transfer in cells and the genetic and biomechanisms that underlie cell growth and cancer induction. Emergent diseases such as AIDS and adult T-cell lymphona have widened even further the community of investigators directly concerned with retroviruses, a development that has highlighted the need for an integrated understanding of their biology and their unique association with host genomes. This volume aims to satisfy that need.