Explores why genetic changes do not cause organisms to fail catastrophically and how evolution shapes organisms' robustness. This book looks at this problem, starting with the alphabet of DNA, the genetic code, RNA, and protein molecules, moving on to genetic networks and embryonic development, and working his way up to whole organisms.
Wagner's treatise is more than good biology; it is also very interesting biology. The picture is painted by talented hands... If I have a favorite aspect of the book, it is the meticulous yet insightful analysis of neutral spaces and their relevance for the main themes of the book. -- Eors Szathmary Nature Wagner contributes significantly to the emerging view that natural selection is just one, and maybe not even the most fundamental, source of biological order. His two-page epilogue throws out seven open questions for systems biologists and neo-Darwinians to consider; hopefully they will do so. g Gibson," Science This book is invaluable for everybody interested in robustness... I predict that for many years to come, Wagner's book will be the bibliographic reference work of choice for research on robustness. -- Claus O. Wilke BioScience Unparalleled in its field, this book offers the most detailed analysis available of all facets of robustness within organisms. It will appeal not only to biologists but also to engineers interested in the design of robust systems and to social scientists concerned with robustness in human communities and populations. Ethnology, Ecology, and Evolution
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