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The Telomore

By: David Kipling

207 pages, 17 illus

Oxford University Press

Paperback | Jan 1995 | #41380 | ISBN: 0199636001
Availability: Usually dispatched within 2-3 weeks Details
NHBS Price: £84.99 $111/€96 approx
Hardback | Dec 1995 | #41379 | ISBN: 019963467X
Out of Print Details

About this book

Contents include: the role of telomeres in nuclear organisation; telomere DNA sequence and unusual structures formed by telomeric sequences in vitro; replication of telomere sequences by telomerase and how this relates to various DNA sequence features; proteins that bind or interact with telomeres; etc.

"Kipling employs a broad selection and insightful discussion of current reviews and primary references to introduce the reader to telomeres. . .those new to this specialized area will appreciate the author's knowledgeable evaluation of how well the research cited supports certain models of telomere behavior." --Choice
"(Kipling) has produced an incisive and captivating account with material of interest to a broad spectrum of telophiles, from spectators to central players in research....The Telomere is rigorous in summary, bold in speculation, and near comprehensive in scope....a gripping read." --Science


Introduction; 1. The cytology of the telomere; 2. Telomere structure; 3. Telomerase; 4. Telomere proteins; 5. Genome rearrangements and telomeres; 6. Human telomere loss, ageing, and cancer; 7. Chromatin structure and position effects; 8. Structure and maintenance of Drosophila telomeres; 9. Telomeres and mammalian genome analysis

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