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About this book
Contents include: the role of telomeres in nuclear organisation; telomere DNA sequence and unusual structures formed by telomeric sequences in vitro; replication of telomere sequences by telomerase and how this relates to various DNA sequence features; proteins that bind or interact with telomeres; etc.
Introduction; 1. The cytology of the telomere; 2. Telomere structure; 3. Telomerase; 4. Telomere proteins; 5. Genome rearrangements and telomeres; 6. Human telomere loss, ageing, and cancer; 7. Chromatin structure and position effects; 8. Structure and maintenance of Drosophila telomeres; 9. Telomeres and mammalian genome analysis