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Biopharmaceuticals in Plants: Toward the Next Century in Medicine

By: Kathleen Laura Hefferon

224 pages, b/w & col illus

CRC Press

Hardback | Nov 2009 | #184809 | ISBN-13: 9781439804742
Availability: Usually dispatched within 6 days Details
NHBS Price: £63.99 $84/€73 approx

About this book

This book provides a comprehensive survey of all major aspects of the development and production of plant-made biopharmaceuticals.

This book serves as an excellent introduction to biopharmaceuticals and as a source of references for those wanting more details. --Monique S.]. Simmonds, in The Journal of Experimental Agriculture, 2011, volume 47 (I) "Today, molecular farming represents an extremely heterogeneous field, due to the large variety of different production hosts examined and further complications derived from the different cultivation systems employed. ...the book provides a comprehensive overview of the different approaches taken over the last 20 years since the first heterologous expression of a monoclonal antibody in tobacco." --Dr. Stefan Jennewein, Fraunhofer Institute for Molecular Biology and Applied Ecology, in ChemMedChem, 2010.


History of Plants in Production of Biopharmaceuticals. Transgenic Plants Expressing Vaccine and Therapeutic Proteins. Chloroplast Engineering and Production of Biopharmaceuticals. Plant Viral Expression Vectors and Production of Biopharmaceuticals in Plants. Glycosylation of Therapeutic Proteins in Plants. Scale-Up of Plant-Derived Pharmaceuticals; the Prospects for Commercial Production and for Global Health. The Immune Response to Plant-Derived Biopharmaceuticals. Risk Analysis and Safety of Plant-Made Biopharmaceuticals. Epilogue: The Future.

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Kathleen Laura Hefferon achieved her Ph.D. at the University of Toronto. She most recently held the title of Director of Operations of the Human Metabolic Research Unit in the Division of Nutritional Sciences at Cornell University. She also acts as a science writer for the Center for Hepatitis C Research at Rockefeller University in New York City and as an expert selector for the Infection and Immunity Division of the Medical Research Council, in London.

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