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Synthesises foundational concepts, techniques and challenges distinctive to biomolecular sequence analysis, biopolymer structure analysis and prediction, and genomic analysis and evolution.
Foreword Contributors Introduction: Computational Biology in 14 Brief Paragraphs A.K. Konopka and M.J.C. Crabbe BIOMOLECULAR SEQUENCE ANALYSIS Introduction to Pragmatic Analysis of Nucleic Acid Sequences A.K. Konopka Motifs in Sequences: Localization and Extraction M. Crochemore and M-F. Sagot Protein Sequence Analysis and Prediction of Secondary Structural Features J. Heringa BIOPOLYMER STRUCTURE CALCULATION AND PREDICTION Discrete Models of Biopolymers P. Schuster and P.F. Stadler Protein Structure Folding and Prediction W.R. Taylor DNA-Protein Interactions: Target Prediction A. Sarai and H. Kono GENOME ANALYSIS AND EVOLUTION Methods of Computational Genomics: An Overview F. Lisacek Computational Aspects of Comparative Genomics W. Makalowski and I. Makalowska Computational Methods for Studying the Evolution of the Mitochondrial Genome C. Saccone and G. Pesole Appendix 1: Computational Biology: Annotated Glossary of Terms A.K. Konopka, P. Bucher, M.J.C. Crabbe, M. Crochemore, J. Heringa, F. Lisacek, I. Makalowska, G. Pesole, C. Saccone, M-F. Sagot, A. Sarai, P. Stadler, and W.R. Taylor Appendix 2: A Dictionary of Programs for Sequence Analysis A.K. Konopka and J. Heringa Index