The neotropical genera Autophylla Warren, Auophyllodes Prout, Leptolopha Warren, Oospila Warren, Oospiloma Prout, Progonodes Warren, Racheolopha Warren, Rhombochlora Warren, and Urucumia Prout are united into a single genus and their species are taxonomically revised and described. All primary types available have been examined. The revised genus Oospila is a monophyletic group defined by the apomorphic character of the fusion of the juxta and transtilla to form what is here termed an anellar complex. Seventy-four species of Oospila are treated, of which one is described as new. Fourth-eight species-group names are synonymized and 24 species are recombined with Oospila. The adult moths are illustrated and line drawings of the genitalia are provided for all species.