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The study of the control of cell growth is of particular importance for the understanding of cancer and various developmental abnormalities. This book considers both internal and external regulators of cell division, and addresses therapeutic applications and structure-function relationships. This book will be of interest to both cell biologists and biomedical researchers.
The Growth-Inhibitory Effects of TGFB; The Retinoblastoma Family and Growth Control; The Growth Regulatory Role of p21(WAF1/GIP1); Mechanisms of Cell Cycle Blocks at the G2/M Transition; Mechanisms of Interferon Action; Growth-Inhibiting N-Substituted Endogenous Peptides; Endogenous Angiogenesis Inhibitors: Angiostatin, Endostatin, and Other Proteolytic Fragments; Inhibitors of Preadipocyte Replication: Opportunities for the Treatment of Obesity; Growth Inhibitors for Mammary Epithelia Cells; Growth Inhibition of Human Fibroblasts in vitro.