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Intercellular Signaling in Development and Disease: Cell Signaling Collection Volume 4

Series: Cell Signaling Collection Volume: 4

Edited By: Edward A Dennis and Ralph A Bradshaw

540 pages, colour illustrations

Academic Press

Paperback | Apr 2011 | #195147 | ISBN-13: 9780123822154
Availability: Usually dispatched within 1-2 weeks Details
NHBS Price: £57.99 $76/€66 approx

About this book

This title is required reading for anyone involved in cell signaling research with articles written and edited by experts in the field. This title covers disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, and inflammatory bowel disease, along with up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease. This title contains articles written and edited by experts in the field. This is a thematic volume covering disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, and inflammatory bowel disease. It provides up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease.

The Cell Signaling Collection consists of four independent volumes which reprint articles from the second edition of the 'Handbook of Cell Signaling' carefully selected to alert medical and biological scientists to recent developments in the study of cellular signaling. This volume contains 57 articles exploring transduction mechanisms. After an overview of intracellular signaling, they cover phosporylation and dephosphorylation in kinases and phosphates, lipid signaling, cyclic nucleotides, and G proteins. The other volumes cover the functioning of transmembrane receptors, the regulation of organelle and cell compartment signaling, and intracellular signaling in development and disease.
- Reference and Research Book News

"For professionals, graduate researchers, and graduate students in biochemistry, biology, genetics, and biomedicine, Dennis (chemistry and biochemistry and pharmacology, U. of California, San Diego) and Bradshaw (chemistry and pharmaceutical chemistry, U. of California, San Francisco) bring together 52 articles from the authors' 'Handbook of Cell Signaling' on cell-cell signaling, signaling development, and signaling in disease. A group of biologists, chemists, oncologists, surgeons, and other scientists from the US, Europe, Singapore, and Australia emphasize the role of cell-cell interaction and organ and tissue effects in signaling activities and their disease implications. They do not cover other aspects of cell signaling like transmembrane receptor structure, receptor organization and function, intracellular signaling mechanisms, and transcriptional activation and responses in other organelles."
- Reference and Research Book News


294. Protein Quality Control in the Endoplasmic Reticulum
295. Quality Control and Quality Assurance in the Mitochondrion
296. Protein Quality Control in Peroxisomes: Ubiquitination of the Peroxisomal Targeting Signal Receptors
297. Mitochondrial Dynamics: Fusion and Division
298. The SREBP Pathway: Gene Regulation through Sterol Sensing and Gated Protein Trafficking
299. Regulating Endoplasmic Reticulum Function through the Unfolded Protein Response
300. Signaling Pathways from Mitochondria to the Cytoplasm and Nucleus
301. Apoptosis Signaling: A Means to an End
302. Regulation of Cell Cycle Progression
303. Signaling During Organelle Division and Inheritance: Peroxisomes
304. Signaling at the Nuclear Envelope
305. Bidirectional Crosstalk between Actin Dynamics and Endocytosis
306. Signaling in Autophagy Related Pathways

Cell-Cell and Cell-Matrix Interaction
307. Overview of Cell-Cell and Cell-Matrix Interactions
308. Interactive Signaling Pathways in the Vasculature
309. Signaling Pathways Involved in Cardiogenesis
310. Regulatory Signaling in Pancreatic Organogenesis: Implications for Aberrant Signaling in Pancreatic Cancer
311. Trophic Effects of Gut Hormones in the Gastrointestinal Tract
312. The Neurotrophin Factors
313. Cell to Cell and Cell-Matrix Interactions in Bone
314. Cell-Cell Signaling in the Testis and Ovary
315. Signal Transduction in T Lymphocytes
316. Signal Transduction via the B Cell Antigen Receptor: A Crucial Regulator of B Cell Biology
317. Signaling Pathways in the Normal and Neoplastic Breast
318. Kidney
319. Cytokines and Cytokine Receptors Regulating Cell Survival, Proliferation, and Differentiation in Hematopoiesis
320. Signaling Pathways Regulating Growth and Differentiation of Adult Stem Cells
321. In Vivo Imaging of Cellular Network Signaling

Disease Pathophysiology: Translational Implications
322. The Roles of Ras Family Small GTPases in Breast Cancer
323. Translational Implications of Stromal-Epithelial Interactions in Prostate Cancer and the Potential Role of Prostate Cancer Stem/Progenitor Cells
324. Aberrant Signaling Pathways in Pancreatic Cancer: Opportunities for Targeted Therapeutics
325. The Evolution and Maintenance of the Multiple Myeloma Cell Clone within the Liquid Bone Marrow Compartment: Therapeutic Implications
326. The Pathophysiologic Role of the Bone Marrow Environment and its Niches in Multiple Myeloma
327. Signaling Targets in Myeloid Leukemias
328. Signaling Targets in Lymphoid Leukemias
329. Targeting Ras for Anticancer Drug Discovery
330. Targeting EWS/FLI1 Driven Signaling Pathways as Therapy for Tumors of the Ewing's Sarcoma Family
331. IRS-Protein Scaffolds and Insulin/IGF Action in Central and Peripheral Tissues
332. Adipokine Signaling: Implications for Obesity
333. Angiogenesis Signaling Pathways as Targets in Cancer Therapy
334. CXC Chemokine Signaling in Interstitial Lung Diseases
335. Systemic Sclerosis
336. Signal Transduction in Rheumatoid Arthritis and Systemic Lupus Erythematosus
337. Translational Concepts in Vasculitis
338. Advances in Understanding the Pathogenesis of Infl ammatory Bowel Disease
339. Translational Implications of Proteomics
340. Translational Implications of microRNAs in Clinical Diagnostics and Therapeutics

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Edward A. Dennis is Distinguished Professor and former Chair of the Department of Chemistry and Biochemistry and Professor in the Department of Pharmacology in the School of Medicine at the University of California, San Diego. He is also Editor-in-Chief of the "Journal of Lipid Research".

Ralph A. Bradshaw is Professor of Chemistry and Pharmaceutical Chemistry; and Deputy Director, Mass Spectrometry Facility, University of California, San Francisco, as well as Professor Emeritus, Department of Physiology and Biophysics, College of Medicine, University of California, Irvine, Irvine, CA. He is also Editor of the journal "Molecular Cellular Proteomics".

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