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Domino reactions enable you to build complex structures in one-pot reactions without the need to isolate intermediates. This book summarizes the possibilities of this reaction type, an approach for an efficiant, economically benificial and ecological
benign synthesis.
Audience: organic chemists.
Introduction Cationic domino reactions Anionic domino reactions Radical domino reactions Pericyclic domino reactions Photochemically induced domino processes Transition metal catalysis Domino reactions initiated by oxidation or reduction Enzymes in domino reactions Multicomponent reactions Special techniques in domino reactions
Lutz F. Tietze studied chemistry at the universities of Freiburg and Kiel, Germany and obtained his doctorate under the supervision of Prof. B. Franck in 1968. He then worked as a research associate with Prof. G. Buchi at MIT, Cambridge, USA, as well as with Prof. A. Battersby in Cambridge, UK. Since 1978 he has been Professor and Head of the Institute of Organic and Biomolecular Chemistry at the Georg-August-University in Gottingen. His research focuses on the development of efficient and selective synthetic methods, combinatorial chemistry, the total synthesis of natural products and the design of new selective anticancer agents. Professor Tietze has been awarded several prizes, including the award for his book on "Reactions and Syntheses" by the Fonds der Chemischen Industrie, the Grignard-Wittig Prize of the Societe Francaise de Chimie and the highly prestigious Emil Fischer Medal of the German Chemical Society. He is President of the German Zentralverband der Chemie and a member of the Council of the German Research Association. He has over 360 papers, 31 patents and three books to his name. Gordon Brasche, born in 1976 in Wernigerode, Germany, studied chemistry at the University of Gottingen, gaining his diploma and doctorate under the supervision of Prof. Tietze with a thesis on the synthesis of new highly active analogous of spinosynes. During his doctorate he worked as a teaching assistant for medical and advanced organic chemistry students. Kersten Matthias Gericke, born in 1976 in Wilhelmshaven, Germany, studied chemistry at the University of Gottingen. He gained his diploma and doctorate under Prof. Tietze, achieving several total syntheses of biological highly potent anthraquinone antibiotics. He also was a teaching assistant for medical and advanced organic chemistry students.
...of considerable interest to all practitioners...particularly valuable to graduate students and postdoctoral fellows... (Journal of the American Chemical Society, June 13, 2007) "This is a book that all serious synthetic organic chemists should add to their personal library." (Chemistry World, March 2007) "Every chemical library should contain this book so that every organic chemist can use it as a source of reference." (Synthesis, February 2007)
