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ds RNA Genetic Elements: Concepts and Applications in Agriculture, Forestry, and Medicine

Edited By: Stellos M Tavantzis

284 pages, Bw plates, figs, tabs

Lewis Publishers

Hardback | Dec 2001 | #119728 | ISBN: 0849322057
Availability: Usually dispatched within 6 days Details
NHBS Price: £127.00 $166/€141 approx

About this book

Our understanding of the nature, origin, and biological roles of double-stranded RNA found in fungi, plants, and animals has advanced greatly during the last five years. Because these genetic elements are capable of replication, they can be used to manage fungal diseases of crops, vegetables, turfgrass, fruit, and forest trees using genetic means rather than by environmentally hazardous chemicals. And recent evidence suggests that the presence of small amounts of dsRNA elicits sequence-specific gene silencing, which may lead to the development of treatments aimed at silencing harmful genes causing serious diseases in animals and humans.dsRNA Genetic Elements: Concepts and Applications in Agriculture, Forestry, and Medicine compiles and unifies current knowledge of dsRNA genetic factors from different biological systems and discusses high-impact applications to agriculture, forestry, and medicine. It is a compilation of the latest advances on dsRNA systems from yeast, filamentous fungi, plants, and animals. This authoritative text is a valuable source of knowledge for a diverse audience from many areas of biology including molecular biology, genetics, and virology, as well as from applied fields in agriculture, forestry, and pharmaceutics.


RNAi and cosuppression: double-stranded RNA as an agent of sequence-specific genetic silencing in animals and plants. Molecular basis of symptom expression by the Cryphonectria hypovirus. Engineering hypovirus for fundamental and practical applications. Double-stranded RNA viruses of Saccharomyces cerevisiae. The double-stranded RNA viruses of Ustilago maydis and their killer toxins. Double-stranded RNA elements modulating virulence in Rhizoctonia solani. Viruses of the Dutch elm disease fungi. Molecular genetics of the viruses infecting the plant pathogenic fungus helminthosporium victoriae. Double-stranded RNAs in the commercial mushroom Agaricus bisporus: Perplexing duplexes on the brink of resolution. Regulation of apoptosis by the double-stranded RNA activated protein kinase PKR.

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