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Proteoglycans: Methods and Protocols

Handbook / Manual

Series: Methods in Molecular Biology Volume: 836

By: Françoise Rédini(Editor)

373 pages, 16 colour & 44 b/w illustrations, 10 tables

Humana Press

Hardback | Jan 2012 | #205446 | ISBN-13: 9781617794971
Availability: Usually dispatched within 1 week Details
NHBS Price: £108.00 $138/€120 approx

About this book

Now recognized as a reservoir for growth factors and cytokines modulating cell activation status and turnover, proteoglycans have stimulated great amount of interest and research. In Proteoglycans: Methods and Protocols, experts in the field examine issues of basic concepts and up-to-date analysis methods for proteoglycan and glycosaminoglycan (GAG) at the protein and saccharide levels.

Proteoglycans: Methods and Protocols continues with the multifunctional aspect of proteoglycans, highlighted through three relevant examples of proteoglycans with highly different strucutures: serglycin, aggrecan, and heparin sulphate proteoglycans. The final chapter describes proteoglycan involvement in the pathogenesis of various disorders and their potential therapeutic value in osteo-articular diseases.

Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Proteoglycans: Methods and Protocols is an ideal guide for scientists attempting to pursue further research in this vital and complex area of study.


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