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Metabolic disorders in humans are considered as a major disease burden in the developed as well as the developing world. Hyperlipidemia is a metabolic disorder characterized by elevated levels of lipids (fats) including cholesterol and triacylglycerol, circulating in the blood and causing serious complications in the cardiovascular system. Medicinal plants and their active components provide an exciting opportunity and promise for new therapeutic approaches to the treatment of hyperlipidemia and constitute an alternative tool to other pharmacological agents.
Based on this rationale, the present volume presents 19 review articles compiling recent data on worldwide studies on medicinal plants broadly directed towards discovery of new drugs of plant origin. The included articles provide an insight into the phytochemical components of plants that contribute to antihyperlipidemic effects, including Acorus calamus, Allium cepa, Allium sativum, Amaranthus spinosus, Camellia sinensis, Catharanthus sinensis, Citrus medica, Emblica officinalis, Moringa oleifera, Picrorhiza kurroa, Piper lungum, Piper nigrum, Premna mucronata, Pterocarpus marsupium, Terminalia belerica, Terminalia arjuna, Trigonella foenum-graecum, and Zingiber officinale. These plants can promote reduction of lipid levels in the blood and help in the process of controlling the levels of low-density lipoprotein (LDL), TC and HDL cholesterol. Several of them act as a potential source of bioactive metabolites for the CHDs.
The content of this volume indicates the current progress by reviewing the role of herbal medicines for hyperlipidemic disorders. The first few chapters in the volume reveal the various pathophysiological processes of hyperlipidemia and regulatory mechanism of cholesterol with multiple lipoproteins. The volume briefly summarizes the medicinal values of a few selected plants characterized for phytochemistry, pharmacological actions, biological efficacy, toxicological and safety reference and proven potential with molecular mechanism for the management and treatment of hyperlipidemia. The volume is aimed at a wide range of audience of ethnobotanists, phytochemists, pharmacologists, pharmacists, pharmacognosists and other research scientists engaged in the search for new drugs from natural resources for the treatment of hyperlipidemia treatment.
- About the Series
- Foreword to the Series
- Foreword to the Volume
- About the Editors
- Pathophysiology of Hyperlipidemia: Current and Future Perspectives
- Therapeutic Investigation of Acorus calamus in Triton X-100 Induced Hyperlipidemia in Rats
- Allium cepa L.: A Scientifically Validated Medicinal Plant for the Prevention and Treatment of Hyperlipidemia
- Antihyperlipidemic Potential of the Functional Leafy-Vegetable: Amaranthus spinosus L.
- Antihyperlipidemic Activity of Citrus medica
- Emblica officinalis Gaertn.: A Review of Application with Special Reference to Hyperlipidemia
- Moringa oleifera Bioactives and its Relationship with Dyslipidemias by AMPK Regulation
- Moringa oleifera: Importance in Hyperlipidemia and its Biological Overview
- Picrorhiza kurroa: A Plant of High Pharmacological Importance
- Piper longum - An Ayurvedic Remedy as Antihyperlipidemic
- Efficacy of Piperine from Piper nigrum in Metabolic Disorders: A Review
- Premna mucronata Roxb: A Review on its Isolation, Structural Elucidation and in Relation to Hyperlipidemia
- Evaluation of Anti-Obesity Potential of Heartwood of Pterocarpus marsupium Using Pancreatic Lipase Inhibitory Activity and High Fat Diet Model in Rats
- In vitro Hmg-Coa Reductase Inhibitory Effect and Kinetic Properties of Terminalia arjuna (Roxb.) Wight & Arn
- Hyperlipidemic Potentials of Terminalia belerica
- Trigonella foenum-graecum as Antihyperlipidemic Agent
- Beneficial Effects of Zingiber officinale Ugainst Hyperlipidemia
- Efficacy Study and Safety Evaluation of Isolated Active Compounds of Some Indian Medicinal Plants with Respect to Regulation of Cardiovascular Problems