Books  Animal & General Biology  Biochemistry & Molecular Biology 

Transplantation Immunology: Methods and Protocols

Handbook / Manual

Series: Methods in Molecular Biology

By: Marlene Rose and Philip Hornick

Humana Press

Hardback | Dec 2006 | #163702 | ISBN: 1588295443
Availability: Usually dispatched within 1 week Details
NHBS Price: £139.99 $187/€160 approx

About this book

Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.


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